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Beneficial AND Harmful Effects OF Tissue Cells IN THE Human Gut

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Beneficial AND Harmful Effects OF Tissue Cells IN THE Human Gut

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Beneficial AND Harmful Effects OF Tissue Cells IN THE Human Gut

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What Is the Beneficial and Harmful Effects of Tissue Cells in the Human Gut?


A tissue is section of an organism that contains many cells with similar structures and roles. Examples include the connective tissue and nerve tissue cells. The human gut has a number of tissues called the lymphoid tissues throughout the intestine covering the greatest area of the intestine. The main reason behind this is majorly to increase the surface area for the food absorption. The increased surface area is achieved by the intestinal mucosa composed of villi and also covered by the epithelial cells. Below the epithelial cells are other loose connective tissues (lamina propia) (Kim, & Shivdasani, 2016).
Beneficial and Harmful Effects of Tissue Cells in the Human Gut
A great number of the bad bacteria always thrive in the unhealthy tissues and bad cells within the gut. For example, increased consumption of junk food acts as catalysts in the multiplication of the bad gut cells. However, when one observe diet and avoid other alcoholic drinks including other antibiotics, the gut tissue cells will have a great and easy function by providing the optimal conditions. The tissue cells however have a greater role in the human gut including physiological function of food absorption (Bartfeld et al., 2015).
Tissue cell and tissue cell trafficking is always linked with lymphoid tissue as an important aspect in diseases pathogenesis. For example, the inflammatory bowel disease (IBD) is a chronic intestinal disorder where most patients suffer the effects of bleeding, fever and abdominal pains among other disorders. However, when medical examinations are done on the living cells obtained from the patients who show the existence of an active disease, large numbers of leukocytes can be seen. However, during this process, a great injury may be caused to the intestines including loss of the globlet cells or reduced production of mucus that plays a significant role in the functioning of the gut. Despite the fact that there is serious risk of intestinal inflammation, it can on the other hand be recognized that there is a boosted immune system and the tissue cells play a very great role of fighting disease pathogens. Studies done have shown that most serious gut inflammation always arise from dysregulated immune response to the various parts of the commensal flora. It is therefore to understand that for the host organism to control the mobility of the tissue cells in the gut and the lymphoid tissue, all the meristematic tissue then become actively involved (Juge, Tailford, & Owen, 2016).
In order to boost the immune system so as to respond to the enteric pathogens, all the inductive site of the intestinal track must be covered by the intravascular naïve tissue cells. Even though trafficking of the intravascular tissue cells is a complicated process controlled by a number of steps, it always has to be carried out. It’s during this stage that the signaling, adhesion and activation of induced firm adhesion causes an intestinal musical immunity to the bacterial antigens. However, the antigens may enter the Peyer’s patches through a medium called the M cells where they are endocytosed in the dome region (Logan, Jacka, & Prescott, 2016). For successful migration of the naïve tissue cells from blood to other secondary lymphoid, high endothelial venules play a greater role. The most important aspect of the tissue cell trafficking in pathogenesis includes adhesive interactions in the induction of intestinal inflammations. A number of adhesion molecules have greater importance in determining induction of colonic inflammation using self-limiting models of acute colitis (Hayakawa et al., 2015).
In conclusion, the gut bacteria play a vital role in human health and diseases. It’s also evident that the main role of the gut bacteria is the immunoregulatory function in the pathogenesis of disease. On the other hand, lifestyle and diet also makes one to be greatly susceptible to a number of diseases. Also, drugs and other antibiotics influence the bacterial gut population.  However, greater methods such as fecal microbiota transplant have been employed to regulate the gut bacteria. It’s therefore recommended to carry out further studies with the aim of establishing the pathogenesis of the gut bacteria and other related diseases.
On the other hand, for protection from invasion from enteric pathogens, the intravascular tissue cells must traffic the inductive sites of the intestine. Although if the process is not properly controlled, the enteric antigen produces effector cells which in turn increases the chances of serious intestinal inflammation. It is the responsibility of the lymphoid tissues to act as the inductive sites to prime and polarize the naïve tissue cells.
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